Structure of PDB 6r5c Chain B

Receptor sequence
>6r5cB (length=191) Species: 1496 (Clostridioides difficile) [Search protein sequence]
TIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKI
KLLSGKLTDEKEYAYLKGVVPKGFEGTGKTWDDVPGLGGSTVALRIGFSN
KGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNFL
GVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK
3D structure
PDB6r5c Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
ChainB
Resolution1.881 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.89: Pro-Pro endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K101 F103 W110 L116 G117 G118 S119 H134 D135 L139 H142 H146 F178 E185 K72 F74 W81 L87 G88 G89 S90 H105 D106 L110 H113 H117 F149 E156
BS02 ZN B H142 H146 E185 H113 H117 E156
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r5c, PDBe:6r5c, PDBj:6r5c
PDBsum6r5c
PubMed31182482
UniProtQ183R7|PPEP1_CLOD6 Pro-Pro endopeptidase (Gene Name=zmp1)

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