Structure of PDB 6r4x Chain B

Receptor sequence
>6r4xB (length=192) Species: 1496 (Clostridioides difficile) [Search protein sequence]
TTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLK
IKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFS
NKGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNF
LGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK
3D structure
PDB6r4x Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
ChainB
Resolution1.831 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.89: Pro-Pro endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B P100 K101 W103 W110 G115 L116 G117 S119 H134 D135 A136 H142 H146 H150 F178 P72 K73 W75 W82 G87 L88 G89 S91 H106 D107 A108 H114 H118 H122 F150
BS02 ZN B H142 H146 E185 H114 H118 E157
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r4x, PDBe:6r4x, PDBj:6r4x
PDBsum6r4x
PubMed31182482
UniProtQ183R7|PPEP1_CLOD6 Pro-Pro endopeptidase (Gene Name=zmp1)

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