Structure of PDB 6r1c Chain B

Receptor sequence
>6r1cB (length=110) Species: 431944 (Magnetospirillum gryphiswaldense MSR-1) [Search protein sequence]
VLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSL
AQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGL
IKDRLAEGPA
3D structure
PDB6r1c De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C24 C27 C90 C93 C11 C14 C77 C80
BS02 JOW B N50 M54 F77 W79 W85 I87 H96 W99 Y101 N37 M41 F64 W66 W72 I74 H83 W86 Y88 PDBbind-CN: -logKd/Ki=4.92,Ki=12uM
BindingDB: Ki=12000nM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6r1c, PDBe:6r1c, PDBj:6r1c
PDBsum6r1c
PubMed31251063
UniProtA4TVL0

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