Structure of PDB 6r0p Chain B

Receptor sequence
>6r0pB (length=161) Species: 59300 (Getah virus) [Search protein sequence]
KAPSYRVRRADISGHGEEAVVNAANAKGTVSDGVCRAVAKKWPSSFKGAA
TPVGTAKMIRADGMTVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTN
NIKSVAVPLLSTGTFSGGKDRVMQSLNHLFTALDATDADVVIYCRDKNWE
KKIQEAIDRRT
3D structure
PDB6r0p Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JNT B A9 D10 I11 A22 A23 N24 S30 D31 G32 V33 L108 S110 T111 G112 T113 F114 R144 A10 D11 I12 A23 A24 N25 S31 D32 G33 V34 L109 S111 T112 G113 T114 F115 R145
External links
PDB RCSB:6r0p, PDBe:6r0p, PDBj:6r0p
PDBsum6r0p
PubMed32879358
UniProtQ5Y389|POLN_GETV Polyprotein P1234

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