Structure of PDB 6qux Chain B

Receptor sequence
>6quxB (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI
KRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQ
GVDDAFYTLVREIRKHK
3D structure
PDB6qux KRAS Binders Hidden in Nature.
ChainB
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B S17 T35 S17 T35
BS02 JJN B V7 D54 L56 T74 V7 D54 L56 T74 MOAD: Kd=1mM
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qux, PDBe:6qux, PDBj:6qux
PDBsum6qux
PubMed31231840
UniProtP01116|RASK_HUMAN GTPase KRas (Gene Name=KRAS)

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