Structure of PDB 6qtp Chain B

Receptor sequence
>6qtpB (length=189) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
GKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVE
KARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAH
IRTLLLTFFYRFMRPLIEAGYVYIAQPPYKGLGEMNADQLWETTMNPEHR
ALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYA
3D structure
PDB6qtp Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase.
ChainB
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E435 G436 D437 S438 R458 G459 K460 D512 E20 G21 D22 S23 R43 G44 K45 D97
BS02 dna B R458 K460 L462 N463 K466 R471 H515 V626 R629 R43 K45 L47 N48 K51 R56 H100 V175 R178
BS03 MN B E435 D508 E20 D93
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:6qtp, PDBe:6qtp, PDBj:6qtp
PDBsum6qtp
PubMed30757898
UniProtP66937|GYRB_STAAN DNA gyrase subunit B (Gene Name=gyrB)

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