Structure of PDB 6qst Chain B

Receptor sequence
>6qstB (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
KPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDL
STIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVF
EQEIDPVMQSLG
3D structure
PDB6qst Structure of CREBBP bromodomain with compound 2 bound
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JGK B L1120 R1173 L35 R88
BS02 JGK B P1110 Q1113 V1115 L1120 N1168 R1173 V1174 P25 Q28 V30 L35 N83 R88 V89
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6qst, PDBe:6qst, PDBj:6qst
PDBsum6qst
PubMed
UniProtQ92793|CBP_HUMAN CREB-binding protein (Gene Name=CREBBP)

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