Structure of PDB 6q1b Chain B

Receptor sequence
>6q1bB (length=184) Species: 309803 (Thermotoga neapolitana DSM 4359) [Search protein sequence]
MLYDLAKKRKTVRRFKKEKPPLEDLIYSLKVANEAPSGMNAQPWRFLIVE
DEKLKGQIRRVCERSEKTFYENVRGRLKEWLDEKRFTWRKPFLKEAPYLL
LVFSEKSAPYSRESVWLAVGYLLLALEEKGLGSVPYTPPDFREVEKLVNT
PSELRLEVILPVGYPDDPKPKYPRNEVIVRYNTF
3D structure
PDB6q1b Crystal structure of oxidized Tn IYD bound to FMN and 3-fluoro-L-tyrosine
ChainB
Resolution1.596 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.21.1.1: iodotyrosine deiodinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN B P38 S39 G40 N42 E115 S116 P36 S37 G38 N40 E113 S114
BS02 YOF B G40 M41 Y112 G38 M39 Y110
BS03 YOF B E68 Y72 L83 K92 Y138 E66 Y70 L81 K90 Y136
BS04 FMN B K12 T13 R15 W82 F88 W118 V136 P137 Y138 T139 K173 Y174 R176 K10 T11 R13 W80 F86 W116 V134 P135 Y136 T137 K171 Y172 R174
Gene Ontology
Molecular Function
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0072545 L-tyrosine binding
GO:0140616 iodotyrosine deiodinase activity
Biological Process
GO:0006570 tyrosine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6q1b, PDBe:6q1b, PDBj:6q1b
PDBsum6q1b
PubMed
UniProtB9K712|IYD_THENN Iodotyrosine deiodinase (Gene Name=IYD)

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