Structure of PDB 6q0r Chain B

Receptor sequence
>6q0rB (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
EHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGF
SKCGRYVLSYTSSSSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDL
YLTVCEWPSDASKVIVFGFNTRSANMMSDENHRDIYVSTVAVPPPGRCAA
CQDASRAAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSL
VACAVSVH
3D structure
PDB6q0r Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 O6M B T230 F231 Q232 P233 A234 F235 T179 F180 Q181 P182 A183 F184
BS02 ZN B C193 C196 C211 H214 C148 C151 C160 H163
Gene Ontology
Biological Process
GO:0016567 protein ubiquitination

View graph for
Biological Process
External links
PDB RCSB:6q0r, PDBe:6q0r, PDBj:6q0r
PDBsum6q0r
PubMed31686031
UniProtQ66K64|DCA15_HUMAN DDB1- and CUL4-associated factor 15 (Gene Name=DCAF15)

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