Structure of PDB 6ppl Chain B

Receptor sequence
>6pplB (length=665) Species: 9606 (Homo sapiens) [Search protein sequence]
NLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLE
DYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEH
LCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYK
GLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDK
FLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPN
DDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFL
VKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAE
EMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIE
RHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAI
EIYLKLHDNPLPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHL
FAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKDL
SDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLD
PSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRA
NCHKLFPYALAFMPP
3D structure
PDB6ppl Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.
ChainB
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP B K416 H420 K447 K556 K304 H308 K335 K444
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0016407 acetyltransferase activity
GO:0043022 ribosome binding
Biological Process
GO:0001525 angiogenesis
GO:0006474 N-terminal protein amino acid acetylation
GO:0030154 cell differentiation
GO:0043066 negative regulation of apoptotic process
GO:0045893 positive regulation of DNA-templated transcription
GO:0050821 protein stabilization
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0016604 nuclear body
GO:0031415 NatA complex
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ppl, PDBe:6ppl, PDBj:6ppl
PDBsum6ppl
PubMed32042062
UniProtQ9BXJ9|NAA15_HUMAN N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gene Name=NAA15)

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