Structure of PDB 6pnz Chain B

Receptor sequence
>6pnzB (length=293) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTR
TKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIR
HPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNV
LICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVI
ETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVM
HPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
3D structure
PDB6pnz The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
ChainB
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.3.2: aspartate carbamoyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PAL B S75 K78 S75 K78
BS02 PAL B S48 T49 R50 T51 R100 H127 R160 R210 Q212 A253 S48 T49 R50 T51 R100 H127 R160 R210 Q212 A253
Gene Ontology
Molecular Function
GO:0004070 aspartate carbamoyltransferase activity
GO:0016597 amino acid binding
GO:0016740 transferase activity
GO:0016743 carboxyl- or carbamoyltransferase activity
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006520 amino acid metabolic process
GO:0044205 'de novo' UMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6pnz, PDBe:6pnz, PDBj:6pnz
PDBsum6pnz
PubMed
UniProtQ5HGN2|PYRB_STAAC Aspartate carbamoyltransferase catalytic subunit (Gene Name=pyrB)

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