Structure of PDB 6pi1 Chain B

Receptor sequence
>6pi1B (length=346) Species: 1658765 (Marinobacter subterrani) [Search protein sequence]
LGSMKTVFSPLHSRRHVKTELDGGLLIEPHEKPSRAETILARVKDQALGE
ILEPEEFGLGPVKRVHTADYVSFLETCWDEWVAAGKRGEAIPTFWVGRGM
RARLPKDIDGRLGYYSLGADTSISDGTWEAARASANVALTAQKLVAEGER
AAFALCRPPGHHAHADVFGGYCFFNNAAIAAQAFRDQGYGKVAVLDVDFH
HGNGTQAIFYDRSDVLTISLHGDPDLVFPHFLGFEDETGEGDGEAYNLNI
VFPPDTPFSIWSQGLEKACERIRTFAPDALVVALGVDTFEEDPISFFKLT
SGDYLKLGKRLEQLGLPTVFTMEGGYDVDAIGVNAVNVMQGFEGKS
3D structure
PDB6pi1 Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth HalophileMarinobacter subterrani.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D195 H197 D284 D198 H200 D287
BS02 MG B D104 D106 D107 D109
BS03 B3N B D19 D117 H158 H159 Y168 D195 H197 F225 I291 Y323 D22 D120 H161 H162 Y171 D198 H200 F228 I294 Y326 MOAD: ic50=160uM
PDBbind-CN: -logKd/Ki=3.80,IC50=160uM
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006338 chromatin remodeling

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Molecular Function
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Biological Process
External links
PDB RCSB:6pi1, PDBe:6pi1, PDBj:6pi1
PDBsum6pi1
PubMed31436969
UniProtA0A0J7JFD7

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