Structure of PDB 6phr Chain B

Receptor sequence
>6phrB (length=347) Species: 1658765 (Marinobacter subterrani) [Search protein sequence]
PLGSMKTVFSPLHSRRHVKTELDGGLLIEPHEKPSRAETILARVKDQALG
EILEPEEFGLGPVKRVHTADYVSFLETCWDEWVAAGKRGEAIPTFWVGRG
MRARLPKDIDGRLGYYSLGADTSISDGTWEAARASANVALTAQKLVAEGE
RAAFALCRPPGHHAHADVFGGYCFFNNAAIAAQAFRDQGYGKVAVLDVDF
HHGNGTQAIFYDRSDVLTISLHGDPDLVFPHFLGFEDETGEGDGEAYNLN
IVFPPDTPFSIWSQGLEKACERIRTFAPDALVVALGVDTFEEDPISFFKL
TSGDYLKLGKRLEQLGLPTVFTMEGGYDVDAIGVNAVNVMQGFEGKS
3D structure
PDB6phr Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth HalophileMarinobacter subterrani.
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SS9 B E17 D19 D117 H159 Y168 D195 H197 F225 E21 D23 D121 H163 Y172 D199 H201 F229 MOAD: ic50=160uM
PDBbind-CN: -logKd/Ki=6.70,Kd=0.2uM
BS02 ZN B D195 H197 D284 D199 H201 D288
BS03 MG B D104 D106 D108 D110
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006338 chromatin remodeling

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6phr, PDBe:6phr, PDBj:6phr
PDBsum6phr
PubMed31436969
UniProtA0A0J7JFD7

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