Structure of PDB 6pfz Chain B

Receptor sequence

>6pfzB (length=541) Species: 224325 (Archaeoglobus fulgidus DSM 4304)

MNVVVIGGGAAGLKAASRIRRKDGDASITVVEAGKYVSLGRCGLPYYVGG
LVHEVDNLRETTYGAVRDEAYFKKLKNIDVLTETVATEIDRSRKTVKIVR
NGSEDELNYDYLVIATGARPAKPPIEGIEAEGVVTLTSAEEAEKIIEMWE
EGAEKAVVIGAGFIGLESAEALKNLDMEVTVIEMMDRVAPAMLDREMAVL
VENHLREKGVNVVTSTRVEKIVSQDDKVRAVIANGKEYPADVVVVATGIK
PNSELAEKAGLKIGETGAIWVDEYMRTSDESIYAGGDCVETTCLVTGKKI
IAPFGDVANKQGRVIGENITGGRAVFPGVIRTAIFKVFDFTAASAGVNEQ
MAKEAGLDYFTVIAPSPDRAHYYPQANYIRLKLIVEKGSWRVIGAQGVGM
GEVAKRIDVLSTAIQAGMTIDQLANLDLAYAPPYSPALDPVITIANVAMN
KRDGLFEGINVFELKEDIVILDVRSEEERIESEKVIHIPILELRERLDEI
PRDKEIVVVCAIGLRSFEASRILKHAGFKVKILEGGMAFWF

3D structure

• PDB: 6pfz Structural and Kinetic Characterization of Hyperthermophilic NADH-Dependent Persulfide Reductase from Archaeoglobus fulgidus .
• Chain: B
• Resolution: 3.10004 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): V37 C42 L455 F456
• Catalytic site (residue number reindexed from 1): V37 C42 L455 F456

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	COA	B	Y430 N450 L523 F526	Y430 N450 L514 F517
BS02	CA	B	D427 L428	D427 L428
BS03	FAD	B	I6 G7 G9 E32 A33 R41 C42 A86 T116 L136 F163 I164 D287 P303 F304 G305	I6 G7 G9 E32 A33 R41 C42 A86 T116 L136 F163 I164 D287 P303 F304 G305
BS04	COA	B	K14 R18 R21 S38 G40 C42 R313	K14 R18 R21 S38 G40 C42 R313
BS05	CA	B	D306 T332	D306 T332

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:6pfz, PDBe:6pfz, PDBj:6pfz
• PDBsum: 6pfz
• PubMed: 33776585
• UniProt: O29847