Structure of PDB 6pc1 Chain B

Receptor sequence
>6pc1B (length=483) Species: 563041 (Helicobacter pylori G27) [Search protein sequence]
AKITTVIDIGSNSVRLAVFKKTSQFGFYLLFETKSKVRISEGCYAFNGIL
QEIPMQRAVKALSEFKEIALKYKSKKILCVATSAVRDAPNRLEFVARVKK
ACGLQIKIIDGQKEALYGGIACANLLHKNSGITIDIGGGSTACALIEKGK
IKDLISLDVGTIRIKEMFLDKDLDVKLAKAFIQKEVSKLPFKHKNAFGVG
GTIRALSKVLMKRFDYPIDSLHGYEIDAHKNLAFIEKIVMLKEDQLRLLG
VNEERLDSIRSGALILSVVLEHLKTSLMITSGVGVREGVFLSDLLRNHYH
KFPPNINPSLISLKDRFLPHEKHSQKVKKECVKLFEALSPLHKIDEKYLF
HLKIAGELASMGKILSVYLAHKHSAYFILNALSYGFSHQDRAIICLLAQF
SHKKIPKDNAIAHMSAMMPSLLTLQWLSFILSLAENLCLTDSHHLKYTLE
KNKLVIHSNDALYLAKEMLPKLVKPIPLTIEFA
3D structure
PDB6pc1 Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.
ChainB
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 G4P B Y369 K404 Y368 K403
BS02 G4P B R16 K35 R205 K209 L222 R256 G283 R15 K34 R204 K208 L221 R255 G282
BS03 PO4 B S12 T83 S84 E115 G138 S141 S11 T82 S83 E114 G137 S140
Gene Ontology
Molecular Function
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6pc1, PDBe:6pc1, PDBj:6pc1
PDBsum6pc1
PubMed31679177
UniProtB5ZA44

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