Structure of PDB 6p8c Chain B

Receptor sequence
>6p8cB (length=216) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence]
MRPYVILNAAMTLDGKIATATGSSEISGEEDLRRVHELRRECDAIMVGIN
TVLADDPRLTVHRVDAAPGDNPVRVVVDSMARTPPHFRVLNDEAPTVIGV
SESAPPERVAELRKRAEVVVAGTRRVDLHLLLERLHGMGIERLMLEGGST
LNYSMLTGGLVDEVRVCIAPMIVGGRDARTLVDGEGIDEMADAIRLELKR
SYTLGEDLIVEYTVKG
3D structure
PDB6p8c The Crystal Structure of 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus
ChainB
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B A9 A10 I17 G48 I49 N50 T51 D55 V77 S79 R82 R125 V126 E146 G148 S149 T150 L151 S154 R179 A9 A10 I17 G48 I49 N50 T51 D55 V77 S79 R82 R125 V126 E146 G148 S149 T150 L151 S154 R179
Gene Ontology
Molecular Function
GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0009231 riboflavin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6p8c, PDBe:6p8c, PDBj:6p8c
PDBsum6p8c
PubMed
UniProtO26337|RIB7_METTH 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (Gene Name=MTH_235)

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