Structure of PDB 6p3w Chain B

Receptor sequence
>6p3wB (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEY
KLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEV
AEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPA
NCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLN
PPETLNL
3D structure
PDB6p3w Structural basis for the ORC1-Cyclin A association.
ChainB
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B M210 I213 L214 W217 Q254 Y280 I281 T282 D283 T285 M35 I38 L39 W42 Q79 Y105 I106 T107 D108 T110
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function

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Biological Process
External links
PDB RCSB:6p3w, PDBe:6p3w, PDBj:6p3w
PDBsum6p3w
PubMed31309634
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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