Structure of PDB 6p00 Chain B

Receptor sequence
>6p00B (length=519) Species: 68170 (Lentzea aerocolonigenes) [Search protein sequence]
MSGKIDKILIVGGGTAGWMAASYLGKALQGTADITLLQAPDIPTLGVGEA
TMPNLQTAFFDFLGIPEDEWMRECNASYKVAIKFINWRTAGEGTSEAREL
DGGPDHFYHPFGLLKYHEQIPLSHYWFDRLYRGKTVEPFDYACYKEPVIL
DANRSPRRLDGSKVTSYAWHFDAHLVADFLRRFATEKLGVRHVEDRVEHV
QRDANGNIESVRTATGRVFDADLFVDCSGFRGLLINKAMEEPFLDMSDHL
LNDSAVATQVPHDDDANGVEPFTSAIAMKSGWTWKIPMLGRFGTGYVYSS
RFATEDEAVREFCEMWHLDPETQPLNRIRFRVGRNRRAWVGNCVSIGTSS
CFVEPLESTGIYFVYAALYQLVKHFPDKSFNPVLTARFNREIETMFDDTR
DFIQAHFYFSPRTDTPFWRANKELRLADGMQEKIDMYRAGMAINAPNFEE
EFRNLWNNSSYYCVLAGLGLVPDAPSPRLAHMPRATESVDEVFGAVKDQQ
RNLLETLPSLHEFLRQQHG
3D structure
PDB6p00 Structural and Computational Analysis of Laboratory-Evolved Halogenases Reveals Molecular Details of Site-Selectivity
ChainB
Resolution2.249 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.19.9: tryptophan 7-halogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G12 G13 A16 A39 E49 A50 V197 S228 R231 L233 W284 T348 F352 P355 G360 I361 G12 G13 A16 A39 E49 A50 V197 S228 R231 L233 W284 T348 F352 P355 G360 I361
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004497 monooxygenase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6p00, PDBe:6p00, PDBj:6p00
PDBsum6p00
PubMed
UniProtQ8KHZ8|TRP7H_LENAE Tryptophan 7-halogenase RebH (Gene Name=rebH)

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