Structure of PDB 6ozm Chain B

Receptor sequence

>6ozmB (length=245) Species: 10090 (Mus musculus) [Search protein sequence]

ERPPEETLSLWKGEQARLKARVVDRDTEAWQRDPSFSGLQKVGGVDVSFV
KGDSVRACASLVVLSYPELKVVYEDSRMVGLKAPYVSGFLAFREVPFLVE
LVQRLQEKEPDLMPQVVLVDGNGVLHQRGFGVACHLGVLTELPCIGVAKK
LLQVDGLENNALHKEKIVLLQAGGDTFPLIGSSGTVLGMALRSHDHSTKP
LYVSVGHRISLEVAVRLTHHCCRFRIPEPIRQADIRSREYIRRTL

3D structure

PDB

6ozm Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.

Chain

Resolution

2.15 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.26.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	B	H202 S203 T204 K205 F230 R231 R237 R244 R248	H196 S197 T198 K199 F224 R225 R231 R238 R242
BS02	rna	B	D52 S54 F55 Y91 S93 G94 L96 E100 D126 N128 H132 G137 V138 K155 K156 L158 Q159	D46 S48 F49 Y85 S87 G88 L90 E94 D120 N122 H126 G131 V132 K149 K150 L152 Q153
BS03	MN	B	D52 D240	D46 D234
BS04	MN	B	D52 D126	D46 D120

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6ozm, PDBe:6ozm, PDBj:6ozm
PDBsum	6ozm
PubMed	31444105
UniProt	Q8C9A2\|ENDOV_MOUSE Endonuclease V (Gene Name=Endov)

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