Structure of PDB 6oxh Chain B

Receptor sequence
>6oxhB (length=289) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
DSKPQLQRLAADADVDRMCRLLEEDGAFILKGLLPFDVVESFNRELDVQM
AIPPPKGERLLADKYPPHFKYVPNVATTCPTFRNTVLINPVIHAICEAYF
QRTGDYWLSAAFLREIESGMPAQPFHRDDATHPLMHFQPLEAPPVSLSVI
FPLTEFTEENGATEVILGSHRWTEVGTPERDQAVLATMDPGDVLIVRQRV
VHAGGGNRTTAGKPRRVVLAYFNSVQLTPFETYRTMPREMVESMTVLGQR
MLGWRTMKPSDPNIVGINLIDDKRLENVLQLKAADSPAL
3D structure
PDB6oxh Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1).
ChainB
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.38: verruculogen synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 B H129 D131 H205 H126 D128 H202
BS02 AKG B R117 Q126 H129 H205 G207 R218 R114 Q123 H126 H202 G204 R215
Gene Ontology
Molecular Function
GO:0051213 dioxygenase activity
Biological Process
GO:1902181 verruculogen biosynthetic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oxh, PDBe:6oxh, PDBj:6oxh
PDBsum6oxh
PubMed31117657
UniProtQ4WAW9|FTMF_ASPFU Verruculogen synthase (Gene Name=ftmOx1)

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