Structure of PDB 6owc Chain B

Receptor sequence
>6owcB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
RSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNL
ADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHP
GKLLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLK
SIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQ
QHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKSDLLLEMLDA
3D structure
PDB6owc Mutant estrogen receptor alpha (ERa) Y537S covalently bound to H3B-6545.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ND1 B M343 L346 T347 A350 E353 W383 L387 M388 L391 F404 L525 M528 C530 M44 L47 T48 A51 E54 W84 L88 M89 L92 F105 L226 M229 C231
External links
PDB RCSB:6owc, PDBe:6owc, PDBj:6owc
PDBsum6owc
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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