Structure of PDB 6ou1 Chain B

Receptor sequence
>6ou1B (length=255) Species: 9606 (Homo sapiens) [Search protein sequence]
GCGELVWVGEPVTLRTAGKYGVWMRDPKPVYPYTQETTWRIDTVGTDVRQ
VFEYDLISQFMQGYPSKVHILPRPLESTGAVVYNGSLYFQGAGSRTVIRY
DLKTETVKAEKEIPGAGYHGQYPYSWGGYTDIDLAVDENGLWVIYSTNQA
KGNIVLSKLNPETLEVEQTWETNIRKQSVANAFIICGTLYTVSSYTSADA
TVNFAYDTNTGTSKYLDIPFKNRYKYNSMIDYNPLERKLFAWDNGHMVTY
DIKLS
3D structure
PDB6ou1 Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations.
ChainB
Resolution1.878 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA B D380 N428 I477 D478 D133 N181 I230 D231
External links
PDB RCSB:6ou1, PDBe:6ou1, PDBj:6ou1
PDBsum6ou1
PubMed31270212
UniProtQ99972|MYOC_HUMAN Myocilin (Gene Name=MYOC)

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