Structure of PDB 6opx Chain B

Receptor sequence

>6opxB (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]

PQITLWKRPLVTVKIEGQLKEALLDTGADDTIFEEMNLPGRWKPIIIGGI
GGFIKVRQYDQILIEICGHKAIGTVVVGPTPFNVIGRNLLTQIGCTLNF

3D structure

PDB

6opx Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.

Chain

Resolution

2.03 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	D25 T26 G27
Catalytic site (residue number reindexed from 1)	D25 T26 G27
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	017	B	D25 G27 A28 D30 G49 P81 F82	D25 G27 A28 D30 G49 P81 F82	MOAD: Ki=172.7nM

Gene Ontology

	Molecular Function
GO:0004190	aspartic-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

External links