Structure of PDB 6oi5 Chain B

Receptor sequence
>6oi5B (length=405) Species: 9606 (Homo sapiens) [Search protein sequence]
NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGA
GAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYL
IIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAI
FTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKK
YADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEM
LHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP
TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILA
EFDYKAEPLETFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFL
RKLFH
3D structure
PDB6oi5 A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.
ChainB
Resolution2.811 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K173 C201 I389 E392 K418
Catalytic site (residue number reindexed from 1) K132 C160 I348 E351 K377
Enzyme Commision number 1.8.5.8: eukaryotic sulfide quinone oxidoreductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G52 S53 G54 E75 P76 Q83 P84 R117 V118 L145 G146 Y170 K200 C201 G335 D336 T345 A346 A347 P380 G11 S12 G13 E34 P35 Q42 P43 R76 V77 L104 G105 Y129 K159 C160 G294 D295 T304 A305 A306 P339
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0048038 quinone binding
GO:0070224 sulfide:quinone oxidoreductase activity
GO:0071949 FAD binding
GO:0106436 glutathione-dependent sulfide quinone oxidoreductase activity
Biological Process
GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Cellular Component
External links
PDB RCSB:6oi5, PDBe:6oi5, PDBj:6oi5
PDBsum6oi5
PubMed31591036
UniProtQ9Y6N5|SQOR_HUMAN Sulfide:quinone oxidoreductase, mitochondrial (Gene Name=SQOR)

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