Structure of PDB 6o96 Chain B

Receptor sequence
>6o96B (length=84) Species: 8355 (Xenopus laevis) [Search protein sequence]
HRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIR
DAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB6o96 Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R35 R45 I46 G48 R78 K79 T80 R18 R28 I29 G31 R61 K62 T63 PDBbind-CN: Kd=50nM
BS02 dna B P32 R36 R45 P15 R19 R28 PDBbind-CN: Kd=50nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Cellular Component
External links
PDB RCSB:6o96, PDBe:6o96, PDBj:6o96
PDBsum6o96
PubMed30981630
UniProtP62799|H4_XENLA Histone H4

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