Structure of PDB 6o8g Chain B

Receptor sequence

>6o8gB (length=568) Species: 1395 ([Bacillus] caldotenax)

GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNV
IAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYINDEIDKLR
HSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALL
RRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIER
IREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAE
LRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPY
TLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALD
NRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTID
VRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVA
YLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDAD
KEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAI
QEEYNRKHGIVPRTVKKE

3D structure

• PDB: 6o8g Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
• Chain: B
• Resolution: 2.64 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	N66 K67 C91 S141 R289 Q346 R357 T454 K455 S477 R484 N503 L504 F527	N64 K65 C89 S118 R266 Q323 R334 T431 K432 S454 R461 N480 L481 F504
BS02	dna	B	P345 G349 G353 E525 G526 F527	P322 G326 G330 E502 G503 F504
BS03	ADP	B	Y11 E12 Q17 G42 T43 G44 K45 P414 R543	Y9 E10 Q15 G40 T41 G42 K43 P391 R520

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006289 nucleotide-excision repair

Cellular Component

• GO:0009380 excinuclease repair complex

External links

• PDB: RCSB:6o8g, PDBe:6o8g, PDBj:6o8g
• PDBsum: 6o8g
• PubMed: 31549070
• UniProt: P56981|UVRB_BACCA UvrABC system protein B (Gene Name=uvrB)