Structure of PDB 6o8f Chain B

Receptor sequence

>6o8fB (length=591) Species: 1395 ([Bacillus] caldotenax)

VEGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTIS
NVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEA
YVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGS
PEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVV
EIFPASRDEHSIRVEFGDEIERIREVDALTGEVLGEREHVAIFPASHFVC
REEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMG
FSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMY
NGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYEL
EHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVT
TLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVG
INLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIM
YADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI

3D structure

• PDB: 6o8f Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
• Chain: B
• Resolution: 2.81 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	H65 N66 K67 S91 Y92 Y93 Y96 K111 A113 S141 S143 Y146 F249 S304 E307 Q346 M350 T454 K455 S477 R484 I502 N503 L504	H65 N66 K67 S91 Y92 Y93 Y96 K111 A113 S141 S143 Y146 F248 S303 E306 Q345 M349 T453 K454 S476 R483 I501 N502 L503
BS02	dna	B	Y95 Q97 P98 V102 K114 P345 G349 E525 G526 F527	Y95 Q97 P98 V102 K114 P344 G348 E524 G525 F526

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006289 nucleotide-excision repair

Cellular Component

• GO:0009380 excinuclease repair complex

External links

• PDB: RCSB:6o8f, PDBe:6o8f, PDBj:6o8f
• PDBsum: 6o8f
• PubMed: 31549070
• UniProt: P56981|UVRB_BACCA UvrABC system protein B (Gene Name=uvrB)