Structure of PDB 6o7g Chain B

Receptor sequence
>6o7gB (length=60) Species: 9606 (Homo sapiens) [Search protein sequence]
SLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFD
CVSCQPYVVK
3D structure
PDB6o7g Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.364: [histone H3]-lysine(4) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L1504 E1516 L1519 L1520 I1521 Q1522 W1529 E1540 L2 E14 L17 L18 I19 Q20 W27 E38
BS02 ZN B C1507 C1510 H1531 C1534 C5 C8 H29 C32
BS03 ZN B C1523 C1526 C1553 C1556 C21 C24 C51 C54
External links
PDB RCSB:6o7g, PDBe:6o7g, PDBj:6o7g
PDBsum6o7g
PubMed31127101
UniProtO14686|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D (Gene Name=KMT2D)

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