Structure of PDB 6o3t Chain B

Receptor sequence
>6o3tB (length=65) Species: 9606 (Homo sapiens) [Search protein sequence]
PPYSYIALITMAIQNKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLS
LNECFVKVPGSYWTL
3D structure
PDB6o3t Crystal Structure of FOXC2 in Complex with DNA Target.
ChainB
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B S76 Y77 N118 H122 S4 Y5 N43 H47
BS02 dna B L95 R121 H122 S125 K132 G143 S144 L20 R46 H47 S50 K57 G60 S61
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6o3t, PDBe:6o3t, PDBj:6o3t
PDBsum6o3t
PubMed31460188
UniProtQ99958|FOXC2_HUMAN Forkhead box protein C2 (Gene Name=FOXC2)

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