Structure of PDB 6nkj Chain B

Receptor sequence

>6nkjB (length=421) Species: 170187 (Streptococcus pneumoniae TIGR4)

MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILS
DVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIV
VLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEA
KAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAI
LLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTG
GDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKT
LPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSE
IIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLD
RGYYGFHEKLAQLGAKIQRIE

3D structure

• PDB: 6nkj 1.3 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Streptococcus pneumoniae in Complex with (2R)-2-(phosphonooxy)propanoic acid.
• Chain: B
• Resolution: 1.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): K23 N24 C120 R125 D309 R401
• Catalytic site (residue number reindexed from 1): K23 N24 C120 R125 D309 R401
• Enzyme Commision number: 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	0V5	B	R96 C120 T121 R401	R96 C120 T121 R401

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
• GO:0016740 transferase activity
• GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Biological Process

• GO:0008360 regulation of cell shape
• GO:0009252 peptidoglycan biosynthetic process
• GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
• GO:0051301 cell division
• GO:0071555 cell wall organization

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6nkj, PDBe:6nkj, PDBj:6nkj
• PDBsum: 6nkj
• UniProt: Q97NQ4|MURA1_STRPN UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (Gene Name=murA1)