Structure of PDB 6n9w Chain B

Receptor sequence
>6n9wB (length=474) Species: 10760 (Escherichia phage T7) [Search protein sequence]
TYNVWNFGESNGRYSALTARGISKETCQKAGYWIAKVDGVMYQVADYRDQ
NGNIVSQKVRDKDKNFKTTGSHKSDALFGKHLWNGGKKIVVTEGEIDMLT
VMELQDCKYPVVSLGHGASAAKKTCAANYEYFDQFEQIILMFDMDEAGRK
AVEEAAQVLPAGKVRVAVLPCKDANECHLNGHDREIMEQVWNAGPWIPDG
VVSALSLRERIREHLSSSVGLLFSGCTGINDKTLGARGGEVIMVTSGSGM
GKSTFVRQQALQWGTAMGKKVGLAMLQESVEETAEDLIGLHNRVRLRQSD
SLKREIIENGKFDQWFDELFGNDTFHLYDSTDRLLAKLAYMRSGLGCDVI
ILDHISIVVSSDERKMIDNLMTKLKGFAKSTGVVLVVICHLKNPDKGKAH
EEGRPVSITDLRGSGALRQLSDTIIALERNQQGDMPNLVLVRILKCRFTG
DTGIAGYMEYNKETGWLEPSSYSG
3D structure
PDB6n9w Structures and operating principles of the replisome.
ChainB
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R439 N468 R364 N393
BS02 TTP B G315 M316 G317 K318 S319 T320 R504 P511 N512 Y535 K537 G249 M250 G251 K252 S253 T254 R429 P436 N437 Y460 K462
BS03 MG B S319 Q343 S253 Q277
BS04 TTP B R522 F523 G525 R447 F448 G450
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
GO:0039693 viral DNA genome replication
Cellular Component
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n9w, PDBe:6n9w, PDBj:6n9w
PDBsum6n9w
PubMed30679383
UniProtP03692|HELIC_BPT7 DNA helicase/primase (Gene Name=4)

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