Structure of PDB 6n6k Chain B

Receptor sequence
>6n6kB (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
AAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLII
KQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTP
PGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEE
YEFAPKKAASHRALDDISESIKELQFYRNNIFKKKI
3D structure
PDB6n6k A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.
ChainB
Resolution1.418 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.15.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B Y132 R133 Y131 R132
BS02 rna B E17 M18 G20 L21 W64 C65 H69 S111 E114 S138 H162 E16 M17 G19 L20 W63 C64 H68 S110 E113 S137 H161
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6n6k, PDBe:6n6k, PDBj:6n6k
PDBsum6n6k
PubMed31225796
UniProtQ9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial (Gene Name=REXO2)

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