Structure of PDB 6n4n Chain B

Receptor sequence
>6n4nB (length=195) [Search protein sequence]
KKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVS
TATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQA
PQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKG
SAGGPLLCPAGHAVGIFRAAVSTRGVAKAVDFIPVESLETTMRSP
3D structure
PDB6n4n Multi-input chemical control of protein dimerization for programming graded cellular responses.
ChainB
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.21.98: hepacivirin.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1097 C1099 C1145 H1149 C110 C112 C158 H162
BS02 TSV B Q1041 F1043 H1057 D1081 K1136 G1137 A1139 F1154 R1155 A1156 A1157 D1168 Q54 F56 H70 D94 K149 G150 A152 F167 R168 A169 A170 D181
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019087 transformation of host cell by virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6n4n, PDBe:6n4n, PDBj:6n4n
PDBsum6n4n
PubMed31501561
UniProtP26664|POLG_HCV1 Genome polyprotein

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