Structure of PDB 6mqk Chain B

Receptor sequence
>6mqkB (length=265) Species: 9606 (Homo sapiens) [Search protein sequence]
GFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPPTPQTLQLHSLTHVIE
EVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILITRQRH
IPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTME
EREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGA
DQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDIT
HNIHYENYRVIRLNE
3D structure
PDB6mqk A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface.
ChainB
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP B S58 G59 G61 K62 S63 T64 R195 D197 V250 R266 S12 G13 G15 K16 S17 T18 R143 D145 V198 R214
BS02 MG B S63 T89 S17 T39
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6mqk, PDBe:6mqk, PDBj:6mqk
PDBsum6mqk
PubMed32431830
UniProtQ8IYM1|SEP12_HUMAN Septin-12 (Gene Name=SEPTIN12)

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