Structure of PDB 6mk9 Chain B

Receptor sequence
>6mk9B (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PQITLWQRPIVTIKVGGQLREALIDTGADDTIFEEINLPGRWKPKLIGGI
GGFMKVRQYDQIPIEICGHQAIGTVLVGPTPINVIGRNMLTQIGCTLNF
3D structure
PDB6mk9 In vitro selection of highly darunavir-resistant and replication-competent HIV-1 variants by using a mixture of clinical HIV-1 isolates resistant to multiple conventional protease inhibitors.
ChainB
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7O7 B D25 G27 D29 D30 G48 G49 I50 D25 G27 D29 D30 G48 G49 I50
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6mk9, PDBe:6mk9, PDBj:6mk9
PDBsum6mk9
PubMed
UniProtA0A4P8EW36

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