Structure of PDB 6mii Chain B

Receptor sequence
>6miiB (length=589) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFN
ENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRV
IELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP
EDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPS
GQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIY
MKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALAL
ALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTG
KGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRV
AIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNIN
LPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRK
YIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEAL
IRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM
3D structure
PDB6mii DNA translocation mechanism of the MCM complex and implications for replication initiation.
ChainB
Resolution3.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T369 V377 Y386 K430 A431 T354 V362 Y371 K415 A416
BS02 08T B E422 R473 P559 R560 E563 E407 R458 P544 R545 E548
BS03 08T B I303 Y304 P342 G343 T344 A345 K346 S347 Q348 I495 I288 Y289 P327 G328 T329 A330 K331 S332 Q333 I480
BS04 ZN B H144 C149 C171 C174 H138 C143 C165 C168
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0032508 DNA duplex unwinding

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6mii, PDBe:6mii, PDBj:6mii
PDBsum6mii
PubMed31308367
UniProtQ9UXG1|MCM_SACS2 Minichromosome maintenance protein MCM (Gene Name=MCM)

[Back to BioLiP]