Structure of PDB 6mfu Chain B

Receptor sequence
>6mfuB (length=215) Species: 235443 (Cryptococcus neoformans var. grubii H99) [Search protein sequence]
RPINPDVVNRPLVICGPSGTGKSTLLKTLFESQPNTFGFSVSHTTRKPRP
GEENGREYHFVTKEEFMEGVGKGEFLEWAEFGGNCYGTTFAALTALHPRR
CILDIELQGVLQLKAKAPLQTPPLEPVFLFLSPPSISQLKSRLSGRGTET
DASIRKRLDAAKEELRYAKEGKYDVYVVNDDLKVAGEKLEKVAMGWEGWK
TCGDTLPELNLAELD
3D structure
PDB6mfu Crystal structure of a Guanylate kinase from Cryptococcus neoformans var. grubii serotype A in complex with GDP and ADP
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.8: guanylate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP B S44 R48 R51 Y60 E79 F83 Y88 G89 T90 D106 I107 E108 R159 S42 R46 R49 Y58 E77 F81 Y86 G87 T88 D104 I105 E106 R157
BS02 ADP B G21 G23 K24 S25 T26 R144 R148 N181 L184 G19 G21 K22 S23 T24 R142 R146 N179 L182
Gene Ontology
Molecular Function
GO:0004385 guanylate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0006163 purine nucleotide metabolic process
GO:0016310 phosphorylation
GO:0046037 GMP metabolic process
GO:0046710 GDP metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6mfu, PDBe:6mfu, PDBj:6mfu
PDBsum6mfu
PubMed
UniProtJ9VQ84

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