Structure of PDB 6mf6 Chain B

Receptor sequence
>6mf6B (length=239) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
QQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLP
KSRLPKIKHPMIVTKWVDYSFSYQLSTEDIGVLFNNGTTVLRLADAEEFW
YISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLHKDDVFLR
RYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGKLVTYISPSHESTTYP
LVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD
3D structure
PDB6mf6 Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W555 W565 V566 A567 H569 K610 D611 D612 F614 R616 S630 W100 W110 V111 A112 H114 K144 D145 D146 F148 R150 S164
External links
PDB RCSB:6mf6, PDBe:6mf6, PDBj:6mf6
PDBsum6mf6
PubMed32099015
UniProtP32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 (Gene Name=CDC5)

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