Structure of PDB 6mea Chain B

Receptor sequence
>6meaB (length=161) Species: 694007 (Tylonycteris bat coronavirus HKU4) [Search protein sequence]
KYKHTVINNSVTLVLGDAIQIASLLPKCILVNAANRHLKHGGGIAGVINK
ASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHVVGPDARNNED
AALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFEYLLANVTTTTYVVV
NNEDIYNTLAT
3D structure
PDB6mea ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4
ChainB
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APR B D325 A326 A341 N343 G349 G351 I352 L429 S431 A432 G433 I434 F435 V457 N459 D17 A18 A33 N35 G41 G43 I44 L121 S123 A124 G125 I126 F127 V149 N151
External links
PDB RCSB:6mea, PDBe:6mea, PDBj:6mea
PDBsum6mea
PubMed
UniProtP0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab (Gene Name=rep)

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