Structure of PDB 6mb9 Chain B

Receptor sequence
>6mb9B (length=265) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SFATRTSLAADLAALGLAWGDAIMVHAAVSRVGRLLDGPDTIIAALRDTV
GPGGTVLAYADWEARYEDLVDDAGRVPPEWREHVPPFDPQRSRAIRDNGV
LPEFLRTTPGTLRSGNPGASLVALGAKAEWFTADHPLDYGYGEGSPLAKL
VEAGGKVLMLGAPLDTLTLLHHAEHLADIPGKRIKRIEVPFATPTGTQWR
MIEEFDTGDPIVAGLAEDYFAGIVTEFLASGQGRQGLIGAAPSVLVDAAA
ITAFGVTWLEKRFGT
3D structure
PDB6mb9 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B A34 V35 S36 P45 N104 G105 V106 A168 P169 T172 T174 A28 V29 S30 P39 N98 G99 V100 A162 P163 T166 T168
BS02 NMY B Y65 D171 H177 T213 G214 D215 E223 Y59 D165 H171 T207 G208 D209 E217
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6mb9, PDBe:6mb9, PDBj:6mb9
PDBsum6mb9
PubMed30347146
UniProtQ51405

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