Structure of PDB 6m63 Chain B

Receptor sequence
>6m63B (length=358) Species: 6100,266835 [Search protein sequence]
RRGDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEP
GDRMFFVVEGSVSVATNWGNVYITADKQKNGIKANFKIRHNVEGGGVQLA
YHYQQNTPIGDGPVLLPDNHYLSVQSKLSKDPNEKRDHMVLLEFVTAAGI
TLSKGEELFTGVVPILVELDGDVNGHKFSVRGEGEGDATNGKLTLKFICT
TGKLPVPWPTLVTTLVQCFARYPDHMKQHDFFKSAMPEGYIQERTIVFKD
DGTYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNRVNPVELG
PGAFFGEMALISGEPRVATVSAATTVSLLSLHSADFQMLCSSSPEIAEIF
RKTALERR
3D structure
PDB6m63 A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CMP B V71 F330 G331 E332 M333 A334 R341 V342 A343 V345 R382 V64 F305 G306 E307 M308 A309 R316 V317 A318 V320 R357
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0008218 bioluminescence

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Molecular Function

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Biological Process
External links
PDB RCSB:6m63, PDBe:6m63, PDBj:6m63
PDBsum6m63
PubMed36097007
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

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