Structure of PDB 6m5e Chain B

Receptor sequence

>6m5eB (length=581) Species: 9606 (Homo sapiens) [Search protein sequence]

AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAK
TCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNEC
FLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYA
PELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCA
SLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLL
ECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPAD
LPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAK
TYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEY
KFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAED
YLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKE
FNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDF
AAFVEKCCKADDKETCFAEEGKKLVAASQAA

3D structure

PDB

6m5e Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	B	E48 T52 D56 E60	E47 T51 D55 E59
BS02	peptide	B	P303 S304 A307 D308	P302 S303 A306 D307
BS03	peptide	B	T166 E167 Q170 A171 A172	T165 E166 Q169 A170 A171
BS04	JEF	B	R209 K351 S480 L481 V482	R208 K350 S479 L480 V481
BS05	JEF	B	Y150 K195 K199 W214 R257 A291	Y149 K194 K198 W213 R256 A290
BS06	M12	B	V46 F49 N61	V45 F48 N60

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0005504	fatty acid binding
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0015643	toxic substance binding
GO:0016209	antioxidant activity
GO:0019825	oxygen binding
GO:0030170	pyridoxal phosphate binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0051087	protein-folding chaperone binding
GO:0140272	exogenous protein binding
GO:1903981	enterobactin binding

	Biological Process
GO:0009267	cellular response to starvation
GO:0051902	negative regulation of mitochondrial depolarization
GO:0072732	cellular response to calcium ion starvation
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0005794	Golgi apparatus
GO:0031093	platelet alpha granule lumen
GO:0032991	protein-containing complex
GO:0070062	extracellular exosome
GO:0072562	blood microparticle

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6m5e, PDBe:6m5e, PDBj:6m5e
PDBsum	6m5e
PubMed	33183011
UniProt	P02768\|ALBU_HUMAN Albumin (Gene Name=ALB)

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