Structure of PDB 6lz9 Chain B

Receptor sequence
>6lz9B (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
VVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDY
EAWLGIHDVHGRGDEKSKQVLQVSQLVYGPEGSDLVLMKLARPAVLDDFV
STIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQ
LQESEICAGAIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRP
GIFVRVAYYAKWIHKIILTYKVP
3D structure
PDB6lz9 Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies.
ChainB
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q534 D578 E670 G671 D672 Y673
Catalytic site (residue number reindexed from 1) Q40 D84 E167 G168 D169 Y170
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N601 C604 T605 I606 Q681 H682 M684 M686 N107 C110 T111 I112 Q178 H179 M181 M183
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6lz9, PDBe:6lz9, PDBj:6lz9
PDBsum6lz9
PubMed
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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