Structure of PDB 6lvx Chain B

Receptor sequence
>6lvxB (length=771) Species: 9544 (Macaca mulatta) [Search protein sequence]
ARWFPKTLPCDVTLDVKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHI
PDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLT
YLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKEQLTELANIEIL
YLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTL
TELYLYNNMIAEIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCTPCKNNS
PLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLA
KEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRI
RGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVID
LSVNKISPVLEQLYYFRYDKYARSCSCYKYGQTLDLSKNSIFFIKSSDFQ
HLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEE
LRKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSR
TMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSF
LPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTV
PERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQK
TSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVQHTEVTIPYLATDVTC
VGPGAHKGQSVISLDLYTCEL
3D structure
PDB6lvx Structural analysis reveals TLR7 dynamics underlying antagonism.
ChainB
Resolution2.77 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EWL B F351 Y356 F408 F324 Y329 F381
BS02 EWL B D555 L557 G584 I585 T586 D491 L493 G520 I521 T522
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
Biological Process
GO:0002224 toll-like receptor signaling pathway
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lvx, PDBe:6lvx, PDBj:6lvx
PDBsum6lvx
PubMed33060576
UniProtB3Y653

[Back to BioLiP]