Structure of PDB 6li9 Chain B

Receptor sequence
>6li9B (length=458) Species: 9606 (Homo sapiens) [Search protein sequence]
LGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLG
ALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIIC
LSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNI
FTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGL
WAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMT
ATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIY
VAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFS
FAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPI
ISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEV
VPPEEDPE
3D structure
PDB6li9 Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ARG B I43 G45 S46 G47 W230 A231 D233 I14 G16 S17 G18 W201 A202 D204
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015171 amino acid transmembrane transporter activity
GO:0015175 neutral L-amino acid transmembrane transporter activity
GO:0015184 L-cystine transmembrane transporter activity
GO:0015297 antiporter activity
GO:0022857 transmembrane transporter activity
GO:0042605 peptide antigen binding
GO:0046982 protein heterodimerization activity
GO:0180009 broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006865 amino acid transport
GO:0015804 neutral amino acid transport
GO:0015811 L-cystine transport
GO:0055085 transmembrane transport
GO:0065003 protein-containing complex assembly
GO:1902475 L-alpha-amino acid transmembrane transport
GO:1990822 basic amino acid transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0031526 brush border membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:6li9, PDBe:6li9, PDBj:6li9
PDBsum6li9
PubMed32494597
UniProtP82251|BAT1_HUMAN b(0,+)-type amino acid transporter 1 (Gene Name=SLC7A9)

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