Structure of PDB 6lae Chain B

Receptor sequence
>6laeB (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
DYVICEECGKEFMDSYLMNHFDLPTCDNCRDADDKHKLITKTEAKQEYLL
KDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEAL
EEAKEVRQENREKMKQ
3D structure
PDB6lae New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA.
ChainB
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T140 K141 T142 W175 M178 K179 T40 K41 T42 W75 M78 K79
BS02 dna B K151 W175 R211 K51 W75 R111
BS03 ZN B C105 C108 C126 C129 C5 C8 C26 C29
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006289 nucleotide-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6lae, PDBe:6lae, PDBj:6lae
PDBsum6lae
PubMed31962067
UniProtP23025|XPA_HUMAN DNA repair protein complementing XP-A cells (Gene Name=XPA)

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