Structure of PDB 6l2z Chain B

Receptor sequence
>6l2zB (length=324) Species: 373153 (Streptococcus pneumoniae D39) [Search protein sequence]
VQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGK
SFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYA
VYQDATGNAKNIAMDWCKGVGAARVGLLETTYKEETEEGLFGEQAVLCGG
LTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSIS
NTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKL
TAYREQAANLEIEKVGAELRKAMP
3D structure
PDB6l2z Crystal Structure of IlvC, a Ketol-Acid Reductoisomerase, from Streptococcus Pneumoniae.
ChainB
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B Y26 G27 S28 Q29 R49 S53 A81 P82 D83 H108 Y24 G25 S26 Q27 R47 S51 A79 P80 D81 H106
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6l2z, PDBe:6l2z, PDBj:6l2z
PDBsum6l2z
PubMed
UniProtQ04M32|ILVC_STRP2 Ketol-acid reductoisomerase (NADP(+)) (Gene Name=ilvC)

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