Structure of PDB 6koy Chain B

Receptor sequence
>6koyB (length=432) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence]
QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLS
RIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIY
AGTPELSGDPGLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATF
TVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPL
ERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPY
PDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTL
ADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRAT
REEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTA
LLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEP
3D structure
PDB6koy Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
ChainB
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) E303 H322 A323 H326 E345 E388 Y396
Catalytic site (residue number reindexed from 1) E268 H287 A288 H291 E310 E353 Y361
Enzyme Commision number 3.4.11.2: membrane alanyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TRP B L147 I149 L163 E165 E303 H322 H326 E345 F391 Y396 L112 I114 L128 E130 E268 H287 H291 E310 F356 Y361
BS02 ZN B H322 H326 E345 H287 H291 E310
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6koy, PDBe:6koy, PDBj:6koy
PDBsum6koy
PubMed31923495
UniProtQ9RVZ5

[Back to BioLiP]