Structure of PDB 6kjf Chain B

Receptor sequence
>6kjfB (length=400) Species: 500485 (Penicillium rubens Wisconsin 54-1255) [Search protein sequence]
HMDTTFQAAIDTGKINGAVVCATDAQGHFVYNKATGERTLLSGEKQPQQL
DDVLYLASATKLITTIAALQCVEDGLLSLDGDLSSIAPELAAKYVLTGFT
DDESPLDDPPARPITLKMLLTHSSGTSYHFLDPSIAKWRAQYANPENEKP
RLVEEMFTYPLSFQPGTGWMYGPGLDWAGRVVERVTGGTLMEFMQKRIFD
PLGITDSQFYPVTREDLRARLVDLNPSDPGALGSAVIGGGGEMNLRGRGA
FGGHGLFLTGLDFVKILRSLLANDGMLLKPAAVDNMFQQHLGPEAAASHR
AALASPLGPFFRVGTDPETKVGYGLGGLLTLEDVDGWYGERTLTWGGGLT
LTWFIDRKNNLCGVGAIQAVLPVDGDLMADLKQTFRHDIYRKYSAWKGQQ
3D structure
PDB6kjf Structural insights into the catalytic mechanism of lovastatin hydrolase
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIM B A56 S57 F129 Y170 I236 E241 F309 W344 G345 G346 G347 A57 S58 F130 Y171 I237 E242 F310 W345 G346 G347 G348 PDBbind-CN: -logKd/Ki=4.97,Kd=10.8uM
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:6kjf, PDBe:6kjf, PDBj:6kjf
PDBsum6kjf
PubMed
UniProtB6H6L7|PCEST_PENRW Lovastatin esterase (Gene Name=PcEST)

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