Structure of PDB 6kjd Chain B

Receptor sequence
>6kjdB (length=400) Species: 500485 (Penicillium rubens Wisconsin 54-1255) [Search protein sequence]
HMDTTFQAAIDTGKINGAVVCATDAQGHFVYNKATGERTLLSGEKQPQQL
DDVLYLAAATKLITTIAALQCVEDGLLSLDGDLSSIAPELAAKYVLTGFT
DDESPLDDPPARPITLKMLLTHSSGTSYHFLDPSIAKWRAQYANPENEKP
RLVEEMFTYPLSFQPGTGWMYGPGLDWAGRVVERVTGGTLMEFMQKRIFD
PLGITDSQFYPVTREDLRARLVDLNPSDPGALGSAVIGGGGEMNLRGRGA
FGGHGLFLTGLDFVKILRSLLANDGMLLKPAAVDNMFQQHLGPEAAASHR
AALASPLGPFFRVGTDPETKVGYGLGGLLTLEDVDGWYGERTLTWGGGLT
LTWFIDRKNNLCGVGAIQAVLPVDGDLMADLKQTFRHDIYRKYSAWKGQQ
3D structure
PDB6kjd Structural insights into the catalytic mechanism of lovastatin hydrolase
ChainB
Resolution2.299 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LVA B A57 Y127 F129 Y170 I236 E241 H253 F309 G345 G347 A58 Y128 F130 Y171 I237 E242 H254 F310 G346 G348 PDBbind-CN: -logKd/Ki=5.05,Kd=8.9uM
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:6kjd, PDBe:6kjd, PDBj:6kjd
PDBsum6kjd
PubMed
UniProtB6H6L7|PCEST_PENRW Lovastatin esterase (Gene Name=PcEST)

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